Marked Variability of Monacolin Levels in Commercial Red Yeast Rice Products
نویسندگان
چکیده
منابع مشابه
Marked variability of monacolin levels in commercial red yeast rice products: buyer beware!
BACKGROUND Red yeast rice (RYR) is a widely available dietary supplement used by millions of patients as an alternative therapy for hyperlipidemia. It contains 14 active compounds called monacolins that inhibit hepatic cholesterol synthesis. Although studies have suggested that some formulations of RYR may be effective and safe for lipid lowering, monacolin levels are not standardized among mar...
متن کاملTelomerase Inhibitory Effects of Red Pigment Rubropunctatin and Statin Monacolin L Isolated from Red Yeast Rice
In addition to the cholesterol-lowering activity of red yeast rice (RYR), its anticancer activities have been frequently reported. However, the mechanism of action of the anticancer activity of RYR is not yet fully understood. The objective of the current study was to elucidate anticancer compositions and anticancer mechanism of actions of RYR. The isolated compounds from RYR were subjected to ...
متن کاملRed Yeast Rice
Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for a long time in Asian cuisine and traditional medicine. It consists of multiple bioactive substances, including monacolins, which potentially can be used as a nutraceutical. Monacolin K, which is chemically identical to lovastatin, has been recognized as responsible for the cholesterolreducing ef...
متن کاملIn Vivo Hypocholesterolemic Effect of MARDI Fermented Red Yeast Rice Water Extract in High Cholesterol Diet Fed Mice
Fermented red yeast rice has been traditionally consumed as medication in Asian cuisine. This study aimed to determine the in vivo hypocholesterolemic and antioxidant effects of fermented red yeast rice water extract produced using Malaysian Agricultural Research and Development Institute (MARDI) Monascus purpureus strains in mice fed with high cholesterol diet. Absence of monacolin-k, lower le...
متن کاملA simple and rapid approach for removing citrinin while retaining monacolin K in red mold rice.
Monascus species-fermented red mold rice (RMR) has been regarded as a popular hypolipidemic functional food because it contains monacolin K, an inhibitor of de novo cholesterol synthesis. However, the safety of RMR is always an issue because citrinin is present in RMR and is reported to be hepatotoxic and nephrotoxic. The present study was therefore to develop a postprocess to remove citrinin y...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 2010
ISSN: 0003-9926
DOI: 10.1001/archinternmed.2010.382